Select Publications

Block, K. E., Z. Zheng, A. L. Dent, B. L. Kee, and H. Huang. "Gut Microbiota Regulates K/Bxn Autoimmune Arthritis through Follicular Helper T but Not Th17 Cells." J Immunol 196, no. 4 (Feb 15 2016): 1550-7.

Carr, T., V. Krishnamoorthy, S. Yu, H. H. Xue, B. L. Kee, and M. Verykokakis. "The Transcription Factor Lymphoid Enhancer Factor 1 Controls Invariant Natural Killer T Cell Expansion and Th2-Type Effector Differentiation." J Exp Med 212, no. 5 (May 4 2015): 793-807.

Corrales, L., L. H. Glickman, S. M. McWhirter, D. B. Kanne, K. E. Sivick, G. E. Katibah, S. R. Woo, et al. "Direct Activation of Sting in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity." Cell Rep 11, no. 7 (May 19 2015): 1018-30.

Corrales, L., S. R. Woo, J. B. Williams, S. M. McWhirter, T. W. Dubensky, Jr., and T. F. Gajewski. "Antagonism of the Sting Pathway Via Activation of the Aim2 Inflammasome by Intracellular DNA." J Immunol 196, no. 7 (Apr 1 2016): 3191-8.

Guo, X., Y. Liang, Y. Zhang, A. Lasorella, B. L. Kee, and Y. X. Fu. "Innate Lymphoid Cells Control Early Colonization Resistance against Intestinal Pathogens through Id2-Dependent Regulation of the Microbiota." Immunity 42, no. 4 (Apr 21 2015): 731-43.

Jiang, X., J. Bugno, C. Hu, Y. Yang, T. Herold, J. Qi, P. Chen, et al. "Eradication of Acute Myeloid Leukemia with Flt3 Ligand-Targeted Mir-150 Nanoparticles." Cancer Res 76, no. 15 (Aug 1 2016): 4470-80.

Jiang, X., C. Hu, S. Arnovitz, J. Bugno, M. Yu, Z. Zuo, P. Chen, et al. "Mir-22 Has a Potent Anti-Tumour Role with Therapeutic Potential in Acute Myeloid Leukaemia." Nat Commun 7 (Apr 26 2016): 11452.

Kariuki, S. N., J. C. Maranville, S. S. Baxter, C. Jeong, S. Nakagome, C. L. Hrusch, D. B. Witonsky, A. I. Sperling, and A. Di Rienzo. "Mapping Variation in Cellular and Transcriptional Response to 1,25-Dihydroxyvitamin D3 in Peripheral Blood Mononuclear Cells." PLoS One 11, no. 7 (2016): e0159779.

Kubic, J. D., E. C. Little, J. W. Lui, T. Iizuka, and D. Lang. "Pax3 and Ets1 Synergistically Activate Met Expression in Melanoma Cells." Oncogene 34, no. 38 (Sep 17 2015): 4964-74.

Lengyel, E., L. M. Litchfield, A. K. Mitra, K. M. Nieman, A. Mukherjee, Y. Zhang, A. Johnson, et al. "Metformin Inhibits Ovarian Cancer Growth and Increases Sensitivity to Paclitaxel in Mouse Models." Am J Obstet Gynecol 212, no. 4 (Apr 2015): 479 e1-79 e10.

Leventhal, D. S., D. C. Gilmore, J. M. Berger, S. Nishi, V. Lee, S. Malchow, D. E. Kline, et al. "Dendritic Cells Coordinate the Development and Homeostasis of Organ-Specific Regulatory T Cells." Immunity 44, no. 4 (Apr 19 2016): 847-59.

Malchow, S., D. S. Leventhal, V. Lee, S. Nishi, N. D. Socci, and P. A. Savage. "Aire Enforces Immune Tolerance by Directing Autoreactive T Cells into the Regulatory T Cell Lineage." Immunity 44, no. 5 (May 17 2016): 1102-13.

McDonald, B. D., J. J. Bunker, S. A. Erickson, M. Oh-Hora, and A. Bendelac. "Crossreactive Alphabeta T Cell Receptors Are the Predominant Targets of Thymocyte Negative Selection." Immunity 43, no. 5 (Nov 17 2015): 859-69.

Park, S., J. Choi, S. B. Biering, E. Dominici, L. E. Williams, and S. Hwang. "Targeting by Autophagy Proteins (Tag): Targeting of Ifng-Inducible Gtpases to Membranes by the Lc3 Conjugation System of Autophagy." Autophagy 12, no. 7 (Jul 2 2016): 1153-67.

Spranger, S., R. Bao, and T. F. Gajewski. "Melanoma-Intrinsic Beta-Catenin Signalling Prevents Anti-Tumour Immunity." Nature 523, no. 7559 (Jul 9 2015): 231-5.

Stoddart, A., Z. Qian, A. A. Fernald, R. J. Bergerson, J. Wang, T. Karrison, J. Anastasi, et al. "Retroviral Insertional Mutagenesis Identifies the Del(5q) Genes, Cxxc5, Tifab and Etf1, as Well as the Wnt Pathway, as Potential Targets in Del(5q) Myeloid Neoplasms." Haematologica 101, no. 6 (Jun 2016): e232-6.

Verhoef, P. A., M. G. Constantinides, B. D. McDonald, J. F. Urban, Jr., A. I. Sperling, and A. Bendelac. "Intrinsic Functional Defects of Type 2 Innate Lymphoid Cells Impair Innate Allergic Inflammation in Promyelocytic Leukemia Zinc Finger (Plzf)-Deficient Mice." J Allergy Clin Immunol 137, no. 2 (Feb 2016): 591-600 e1.

Zook, E. C., K. Ramirez, X. Guo, G. van der Voort, M. Sigvardsson, E. C. Svensson, Y. X. Fu, and B. L. Kee. "The Ets1 Transcription Factor Is Required for the Development and Cytokine-Induced Expansion of Ilc2." J Exp Med 213, no. 5 (May 2 2016): 687-96.

Acknowledgement of core facility contributions in publications is appreciated.

Cancer Center members should cite the Cancer Center Support Grant (P30CA014599) when publishing any work assisted by this core facility.